API Donepezil HCl CAS 120011-70-3 Bakeng sa Lefu la Alzheimer

Tlhaloso e Khutšoanyane:

Donepezil Hydrochloride ke letsoai la hydrochloride le tsoang ho piperidine e nang le ts'ebetso e matlafatsang methapo ea kutlo.Donepezil e thibela acetylcholinesterase ka mokhoa o fetohang, ka hona e thibela hydrolysis ea neurotransmitter acetylcholine, ka lebaka leo, e eketsa ts'ebetso ea eona.

Ikopanye le: Erica Zheng

Email: erica@zhuoerchem.com

Mohala: +86 21 2097 0332

Mokhopi: +86 177 1767 9251

WhatsApp: +86 186 2503 6043 (WeChat & Telegram & Line)

Skype: slhyzy

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso

Donepezil e sebelisoa ho phekola pherekano e amanang le lefu la Alzheimer's.

Tlhaloso:

Lebitso la Sehlahiswa	Donepezil Hydrochloride
Lebitso la Lik'hemik'hale	1h-inden-1-one,2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)me
Lebitso le Leng	Donepezil hcl;Donezepilhydrochloride;DonepezilHydrochloride(200mg);2-(1-Benzylpiperidin-4-yl)Methyl) -5,6-diMethoxy-2,3-dihydro-1H-inden-1-onehydrochloride;2,3-Dihydrochloride;2,3-Dihydrochloride; -5,6-diMetChemicalbookhoxy-2-[[1-(phenylMethyl)-4-piperidinyl]Methyl]-;2-(1-Benzyl-4-piperidylmethyl) -5,6-dimethoxy-1-indanoneHydrochloride;Donepezil(Aricept );DonepezilHydrochlorideForMⅠ
Nomoro ea CAS	120011-70-3
Foromo ea limolek'hule	C24H30ClNO3
Boima ba Foromo	415.95
Ponahalo	E tiileng ho isa ho bosweu ba kristale
Tlhahlobo	98.0% mets
Melting Point	220-222 °C
Ntlha e belang	527.9 C Ho 760 mmHg
Sephutheloana	20kg/bag/drum, 25kg/bag/drum, kapa kamoo o neng o batla kateng
Polokelo	Boloka setshelo se koetsoe ka thata sebakeng se omeletseng le se phodileng.U se ke ua pepesa mahlaseli a letsatsi.
COA & MSDS	E fumaneha
Kopo	Bakeng sa morero oa lipatlisiso

Setifikeiti sa Tlhahlobo/COA:

LEKANG NTHO	TS'ELISO	RESULT
Ponahalo	Phofo e tšoeu ho isa ho e tšoeu ea kristale	E lumellana
Solubility	E qhibiliha ka bolokolohi ka chloroform, e qhibiliha ka metsing le Acetic acid, e qhibiliha hanyenyane ho Acetonitrile le ethanol, e sa qhibiliheng ho Ethylacetoacetate le n-hexane.	E lumellana
Boitsebiso	(1) Ka ho monya IR, Ho tsamaisana le maemo a sebetsang.	E lumellana
	(2) Nako ea ho boloka tlhōrō e kholo ea sampuli e lokela ho lumellana le ea maemo a sebetsang.	E lumellana
	(3) Teko ea chloride.E arabela tekong ea Chlorides.	E lumellana
Metsi	≤0.4%	0.31%
Masalla ha a tuka	≤0.1%	0.02%
Ntho e amanang le yona	Desbenzyl donepezl^a≤0.15% Analogue ea Donepezil pyridine^b≤0.15% Bromide ea Donepezilzilbenzyl^c≤0.15% Dehydrodeoxy donepezil^d≤0.15% Deoxy donepezil^e≤0.15% Tšilafalo efe kapa efe e sa tsejoeng≤0.10% Kakaretso ≤0.5%	Ha e fumanwe Ha e fumanwe 0.02% Ha e fumanwe Ha e fumanwe 0.05% 0.18%
Tšepe e boima	≤20ppm	≤20ppm
Metsoako e setseng	Methanol≤0.3%Ethanol≤0.5%Ethyl acetate≤0.5% Toluene≤0.089% Acetic acid≤0.5%	Ha e fumanwe Ha e fumanwe Ha e fumanwe Ha e fumanwe Ha e fumanwe
Tlhahlobo	Sebakeng se omisitsoeng, C₂₄H₂₉NO₃·HCl e lokela ho ba 98.0% ho isa ho 102.0%.	99.52%