API Pitavastatin Calcium CAS 147526-32-7

Tlhaloso e Khutšoanyane:

Pitavastatin e sebelisoa hammoho le lijo tse nepahetseng ho thusa ho fokotsa k'holeseterole e "mpe" le mafura (joaloka LDL, triglycerides) le ho phahamisa "cholesterol" e ntle (HDL) maling.

Ikopanye le: Erica Zheng

Email: erica@zhuoerchem.com

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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tlhaloso

Pitavastatin e sebelisoa hammoho le lijo tse nepahetseng ho thusa ho theola k'holeseterole e "mpe" le mafura (joaloka LDL, triglycerides) le ho phahamisa "cholesterol" e ntle (HDL) maling.

Tlhaloso:

Lebitso la Sehlahiswa	Khalsiamo ea pitavastatin
Lebitso la Lik'hemik'hale	calcium;(E,3R,5S) -7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl] -3,5-dihydroxyhept-6-enoate
Lebitso le Leng	PitavasttinCalcium;PitavastatinCalcium/NK-104;(+)-Monocalciunbis{(3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorophenyl-3-quinolyl]-3,5-dihydroxy-6-heptenotate };PitavastatincalciuM(Livalo);Calcium(3R,5S,E) -7-(2-cyclopropyl-Chemicalbook4-(4-fluorophenyl)-quinolin-3-yl) -3,5-dihydroxyhept-6-enoate;(3R ,5S,6E) -7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoicacid,calciumsalt(2:1);NK-104Calcium;PitavastatinCalciuMDIS TSOELA PELE
Nomoro ea CAS	147526-32-7
Foromo ea limolek'hule	C25H26CaFNO4
Boima ba Foromo	463.56
Ponahalo	Tiileng
Tlhahlobo	98.0% mets
Sephutheloana	20kg/bag/drum, 25kg/bag/drum, kapa kamoo o neng o batla kateng
Polokelo	Boloka setshelo se koetsoe ka thata sebakeng se omeletseng le se phodileng.U se ke ua pepesa mahlaseli a letsatsi.
COA & MSDS	E fumaneha

Tšebeliso

Pitavastatin Calcium ke inhibitor ea tlholisano ea enzyme ea HMGCR (HMG-CoA reductase) e fella ka ho fokotseha ha LDL cholesterol synthesis.Liphuputso tse ling li bontša hore pitavastatin e ka hatella tlhahiso ea oksijene liseleng tsa endothelial ka ho thibela NADPH oxidase.Ntle le moo, pitavastatin e fokotsa polelo ea eNOS mRNA ha e ntse e eketsa karabelo e itšetlehileng ka NO e hlohlellelitsoeng ke acetylcholine le calcium ionophore, A23187.Ho feta moo, pitavastatin e thibela ho phahama ha likanale tsa potasiamo tse kentsoeng k'halsiamo ka ho theola boemo ba k'holeseterole liseleng.